University of Guilan Aquatic Animals Nutrition 2980-8499 7 2 2021 06 22 Efficacy of using Sanyar prebiotics in biofloc environment: Evaluation of production performance, water nitrogen compounds, hematological and metabolic responses of common carp, Cyprinus carpio Efficacy of using Sanyar prebiotics in biofloc environment: Evaluation of production performance, water nitrogen compounds, hematological and metabolic responses of common carp, Cyprinus carpio 39 55 5538 10.22124/janb.2022.21549.1162 FA Samira Jafaryan Department of Fisheries, Faculty of Agriculture and Natural Resources, Gonbad Kavous University, Gonbad Kavous, Golestan, Iran Hossein Adineh Department of Fisheries, Faculty of Agriculture and Natural Resources, Gonbad Kavous University, Gonbad Kavous, Golestan, Iran Mohammad Farhangi Department of Fisheries, Faculty of Agriculture and Natural Resources, Gonbad Kavous University, Gonbad Kavous, Golestan, Iran Mohammad Harsij Department of Fisheries, Faculty of Agriculture and Natural Resources, Gonbad Kavous University, Gonbad Kavous, Golestan, Iran Zia Kordjazi Department of Fisheries, Faculty of Agriculture and Natural Resources, Gonbad Kavous University, Gonbad Kavous, Golestan, Iran Journal Article 2021 04 12 The study was performed to find out the potential effects of Sanyar prebiotic on production performance, water nitrogen compounds, blood and metabolic parameters of common carp, <em>Cyprinus carpio</em> reared in a biofloc system. 324 fingerlings (average weight 10.09 ± 0.45 g) were stocked in eighteen 35-L tanks (18 fish in each tank). After 10 days of adaptation to laboratory conditions, six experimental groups were tested for 60 days including: control group without additive with clean water (C), control group without additive with floc (FC), floc groups with 0.1 and 0.2 g (FP₁ and FP₂) prebiotic powder and floc groups with 1 and 2 mL (FL₁ and FL₂) liquid prebiotic per 100 g of basic diet. At the end of the experiment, FP₁ group exhibited significant increase in final biomass weight, final density, and protein efficiency ratio and decrease in feed conversion ratio in comparison with the other groups. Total water ammonia nitrogen was reduced in the C group compared to the FC. Serum urea and creatinine levels increased significantly in the FC group compared to the other experimental groups. ALT, AST and ALP enzymes were significantly increased in groups C and FC compared to the groups fed with Saynar prebiotic. The highest number of red and white blood cells was obtained in FL1 and FC groups, respectively. In conclusion, dietary supplementation of FP1 (0.1 g Sanyar prebiotic per 100 g of basic diet) can be potentially used as health enhancer in common carp reared under biofloc system. The study was performed to find out the potential effects of Sanyar prebiotic on production performance, water nitrogen compounds, blood and metabolic parameters of common carp, <em>Cyprinus carpio</em> reared in a biofloc system. 324 fingerlings (average weight 10.09 ± 0.45 g) were stocked in eighteen 35-L tanks (18 fish in each tank). After 10 days of adaptation to laboratory conditions, six experimental groups were tested for 60 days including: control group without additive with clean water (C), control group without additive with floc (FC), floc groups with 0.1 and 0.2 g (FP₁ and FP₂) prebiotic powder and floc groups with 1 and 2 mL (FL₁ and FL₂) liquid prebiotic per 100 g of basic diet. At the end of the experiment, FP₁ group exhibited significant increase in final biomass weight, final density, and protein efficiency ratio and decrease in feed conversion ratio in comparison with the other groups. Total water ammonia nitrogen was reduced in the C group compared to the FC. Serum urea and creatinine levels increased significantly in the FC group compared to the other experimental groups. ALT, AST and ALP enzymes were significantly increased in groups C and FC compared to the groups fed with Saynar prebiotic. The highest number of red and white blood cells was obtained in FL1 and FC groups, respectively. In conclusion, dietary supplementation of FP1 (0.1 g Sanyar prebiotic per 100 g of basic diet) can be potentially used as health enhancer in common carp reared under biofloc system. https://janb.guilan.ac.ir/article_5538_37368bab6f8696c74b28325b648a364a.pdf